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GIT2 抗体 (AA 450-510)

This anti-GIT2 antibody is a 兔 多克隆 antibody detecting GIT2 in WB. Suitable for 人.
产品编号 ABIN7267315
发货至: 中国

Quick Overview for GIT2 抗体 (AA 450-510) (ABIN7267315)

抗原

See all GIT2 抗体
GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

适用

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宿主

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克隆类型

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多克隆

标记

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This GIT2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 450-510

    原理

    GIT2 Rabbit pAb

    序列

    ASRLEKQNST PESDYDNTPN DMEPDGMGSS RKGRQRSMVW PGDGLVPDTA EPHVAPSPTL P

    交叉反应

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 450-510 of human GIT2 (NP_476511.1).

    亚型

    IgG
  • 应用备注

    WB,1:200 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

    别名

    GIT2

    背景

    This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding.,GIT2,CAT-2,CAT2,PKL,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Kinase,Cell Biology & Developmental Biology,Cytoskeleton,Actins,GIT2

    分子量

    52kDa, 70-84kDa

    基因ID

    9815

    UniProt

    Q14161

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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