FGD5 抗体 (AA 1000-1200)
Quick Overview for FGD5 抗体 (AA 1000-1200) (ABIN7267286)
抗原
See all FGD5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1000-1200
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原理
- FGD5 Rabbit pAb
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序列
- YLGLLSENCL HSPRLAAAVR EFEQSVQGGS QTAKHRLLRV VQRLFQYQVL LTDYLNNLCP DSAEYDNTQG ALSLISKVTD RANDSMEQGE NLQKLVHIEH SVRGQGDLLQ PGREFLKEGT LMKVTGKNRR PRHLFLMNDV LLYTYPQKDG KYRLKNTLAV ANMKVSRPVM EKVPYALKIE TSESCLMLSA SSCAERDEWY G
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交叉反应
- 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1200 of human FGD5 (NP_689749.3).
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亚型
- IgG
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anti-FYVE, RhoGEF and PH Domain Containing 5 (FGD5) (AA 269-539) antibody
FGD5 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FYVE, RhoGEF and PH Domain Containing 5 (FGD5) (AA 1203-1462) antibodyFGD5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FYVE, RhoGEF and PH Domain Containing 5 (FGD5) (AA 1-540) antibodyFGD5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- FGD5 (FYVE, RhoGEF and PH Domain Containing 5 (FGD5))
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别名
- FGD5
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背景
- FGD5 (or ZFYVE23) is an endothelial specific gene, plays a crucial role in vascular pruning. Deficient expression of FGD5 markedly inhibits neovascularization, indicated by in vitro tube-formation, aortic-ring, and coated-bead assays and by in vivo coated-bead plug assays and studies in the murine retina model. FGD5-deficient endothelial cells fail to migrate. Moreover, the cells are susceptible to proapoptotic stimuli associated with VEGF-stimulated activation of Akt. FGD5 promotes apoptosis-induced vaso-obliteration via induction of the hey1-p53 pathway by direct binding and activation of CDC42.,FGD5,ZFYVE23,FYVE,Signal Transduction,G protein signaling,Signal Transduction,FGD5
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分子量
- 61kDa/159kDa
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基因ID
- 152273
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UniProt
- Q6ZNL6
抗原
-
