FREM1 抗体 (AA 1880-2179)
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北京 101111
Quick Overview for FREM1 抗体 (AA 1880-2179) (ABIN7267259)
抗原
See all FREM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1880-2179
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原理
- FREM1 Rabbit pAb
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序列
- GSSSSTTSGS FHLERRPLPS SMQLAVIRGD TLRGFDSTDL SQRKLRTRGN GKTVRPSSVY RNGTDIIYNY HGIVSLKLED DSFPTHKRKA KVSIISQPQK TIKVAELPQA DKVESTTDSH FPRQDQLPSF PKNCTLELKG LFHFEEGIQK LYQCNGIAWK AWSPQTKDVE DKSCPAGWHQ HSGYCHILIT EQKGTWNAAA QACREQYLGN LVTVFSRQHM RWLWDIGGRK SFWIGLNDQV HAGHWEWIGG EPVAFTNGRR GPSQRSKLGK SCVLVQRQGK WQTKDCRRAK PHNYVCSRKL
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1880-2179 of human FREM1 (NP_659403.4).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))
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别名
- FREM1
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背景
- This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon, the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.,FREM1,BNAR,C9orf143,C9orf145,C9orf154,MOTA,TILRR,TRIGNO2,Cell Biology & Developmental Biology,FREM1
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分子量
- 25kDa/42kDa/80kDa/244kDa
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基因ID
- 158326
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UniProt
- Q5H8C1
抗原
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