FGL1 抗体
Quick Overview for FGL1 抗体 (ABIN7267179)
抗原
See all FGL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- FGL1 Rabbit mAb
-
交叉反应
- 人
-
产品特性
- Monoclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant protein of human FGL-1 Full length.
-
亚型
- IgG
-
-
anti-Fibrinogen-Like 1 (FGL1) (AA 23-314) antibody
FGL1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 23-312) antibodyFGL1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4F9C11 unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 23-312) antibodyFGL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 19-312) antibodyFGL1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 23-314) antibodyFGL1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 23-312) antibodyFGL1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 179-282) antibodyFGL1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen-Like 1 (FGL1) antibodyFGL1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen-Like 1 (FGL1) (AA 1-312) antibodyFGL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen-Like 1 (FGL1) antibodyFGL1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB,1:500 - 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.09 % sodium azide,50 % glycerol, pH 7.4.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- FGL1 (Fibrinogen-Like 1 (FGL1))
-
别名
- FGL1
-
背景
- Fibrinogen-like protein 1 (FGL1), a liver-secreted protein, is a major LAG-3 functional ligand independent from MHC-II. The FGL1-LAG-3 pathway maybe an important immune evasion mechanism and could contribute to current cancer immunotherapy efforts for several reasons. FGL1 inhibits antigen-specific T cell activation, and ablation of FGL1 in mice promotes T cell immunity. Blockade of the FGL1-LAG-3 interaction by monoclonal antibodies stimulates tumor immunity and is therapeutic against established mouse tumors in a receptor-ligand inter-dependent manner. FGL1 is highly produced by human cancer cells, and elevated FGL1 in the plasma of cancer patients is associated with a poor prognosis and resistance to anti-PD-1/B7-H1 therapy,FGL1,HFREP1,HP-041,LFIRE-1,LFIRE1,Cardiovascular,Blood,Coagulation,Serum Proteins,FGL1
-
分子量
- 36kDa
-
基因ID
- 2267
-
UniProt
- Q08830
抗原
-
