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FAR1 抗体 (AA 1-220)

This anti-FAR1 antibody is a 兔 多克隆 antibody detecting FAR1 in WB. Suitable for 人.
产品编号 ABIN7267158
发货至: 中国

Quick Overview for FAR1 抗体 (AA 1-220) (ABIN7267158)

抗原

See all FAR1 抗体
FAR1 (Fatty Acyl CoA Reductase 1 (FAR1))

适用

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宿主

  • 22

克隆类型

  • 22
多克隆

标记

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This FAR1 antibody is un-conjugated

应用范围

  • 18
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Western Blotting (WB)
  • 抗原表位

    • 4
    • 2
    • 1
    AA 1-220

    原理

    FAR1 Rabbit pAb

    序列

    MVSIPEYYEG KNVLLTGATG FLGKVLLEKL LRSCPKVNSV YVLVRQKAGQ TPQERVEEVL SGKLFDRLRD ENPDFREKII AINSELTQPK LALSEEDKEV IIDSTNIIFH CAATVRFNEN LRDAVQLNVI ATRQLILLAQ QMKNLEVFMH VSTAYAYCNR KHIDEVVYPP PVDPKKLIDS LEWMDDGLVN DITPKLIGDR PNTYIYTKAL AEYVVQQEGA

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human FAR1 (NP_115604.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    FAR1 (Fatty Acyl CoA Reductase 1 (FAR1))

    别名

    FAR1

    背景

    The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13.,FAR1,MLSTD2,PFCRD,SDR10E1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,FAR1

    分子量

    59kDa

    基因ID

    84188

    UniProt

    Q8WVX9
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