EXOSC10 抗体 (AA 586-885)
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北京 101111
Quick Overview for EXOSC10 抗体 (AA 586-885) (ABIN7267062)
抗原
See all EXOSC10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 586-885
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原理
- EXOSC10 Rabbit pAb
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序列
- VAAGVKKSGP LPSAERLENV LFGPHDCSHA PPDGYPIIPT SGSVPVQKQA SLFPDEKEDN LLGTTCLIAT AVITLFNEPS AEDSKKGPLT VAQKKAQNIM ESFENPFRMF LPSLGHRAPV SQAAKFDPST KIYEISNRWK LAQVQVQKDS KEAVKKKAAE QTAAREQAKE ACKAAAEQAI SVRQQVVLEN AAKKRERATS DPRTTEQKQE KKRLKISKKP KDPEPPEKEF TPYDYSQSDF KAFAGNSKSK VSSQFDPNKQ TPSGKKCIAA KKIKQSVGNK SMSFPTGKSD RGFRYNWPQR
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 586-885 of human EXOSC10 (NP_001001998.1).
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亚型
- IgG
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anti-Exosome Component 10 (EXOSC10) (C-Term) antibody
EXOSC10 适用: 人, 小鼠, Cow, 兔, 大鼠, 犬, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 10 (EXOSC10) (AA 41-140) antibodyEXOSC10 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 10 (EXOSC10) (AA 1-99) antibodyEXOSC10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-Exosome Component 10 (EXOSC10) (C-Term) antibodyEXOSC10 适用: 人, 小鼠, Cow, 兔, 犬, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 10 (EXOSC10) (C-Term) antibodyEXOSC10 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 10 (EXOSC10) (C-Term) antibodyEXOSC10 适用: 人, 小鼠, Cow, 兔, 大鼠, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 10 (EXOSC10) (AA 587-762) antibodyEXOSC10 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Component 10 (EXOSC10) (AA 756-805) antibodyEXOSC10 适用: 人, 小鼠, Cow, 兔, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- EXOSC10 (Exosome Component 10 (EXOSC10))
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别名
- EXOSC10
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背景
- Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs, and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR and/or Ig variable region somatic hypermutation (SHM by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3'-5' exonuclease activity (By similarity. EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of MTREX, C1D and MPHOSPH6 with the RNA exosome involved in the maturation of 5.8S rRNA.,EXOSC10,PM-Scl,PM/Scl-100,PMSCL,PMSCL2,RRP6,Rrp6p,p2,p3,p4,Epigenetics & Nuclear Signaling,RNA Binding,Immunology & Inflammation,EXOSC10
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分子量
- 98kDa/100kDa
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基因ID
- 5394
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UniProt
- Q01780
抗原
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