EDARADD 抗体 (AA 1-215)
This 兔 多克隆 anti-EDARADD antibody specifically detects EDARADD in WB. The antibody is reactive with 人 samples.
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产品编号 ABIN7266900
发货至:
中国
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Quick Overview for EDARADD 抗体 (AA 1-215) (ABIN7266900)
抗原
See all EDARADD 抗体
EDARADD
(EDAR-Associated Death Domain (EDARADD))
适用
人
宿主
兔
克隆类型
多克隆
标记
This EDARADD antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- AA 1-215
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原理
- EDARADD Rabbit pAb
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序列
- MGLRTTKQMG RGTKAPGHQE DHMVKEPVED TDPSTLSFNM SDKYPIQDTE LPKAEECDTI TLNCPRNSDM KNQGEENGFP DSTGDPLPEI SKDNSCKENC TCSSCLLRAP TISDLLNDQD LLDVIRIKLD PCHPTVKNWR NFASKWGMSY DELCFLEQRP QSPTLEFLLR NSQRTVGQLM ELCRLYHRAD VEKVLRRWVD EEWPKRERGD PSRHF
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human EDARADD (NP_665860.2).
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亚型
- IgG
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anti-EDAR-Associated Death Domain (EDARADD) antibody
EDARADD 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- EDARADD (EDAR-Associated Death Domain (EDARADD))
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别名
- EDARADD
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背景
- This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,EDARADD,ECTD11A,ECTD11B,ED3,EDA3,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,EDARADD
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分子量
- 23kDa/24kDa
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基因ID
- 128178
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UniProt
- Q8WWZ3
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途径
- Ubiquitin Proteasome Pathway
抗原
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