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EDARADD 抗体 (AA 1-215)

This anti-EDARADD antibody is a 兔 多克隆 antibody detecting EDARADD in WB. Suitable for 人.
产品编号 ABIN7266900
发货至: 中国

Quick Overview for EDARADD 抗体 (AA 1-215) (ABIN7266900)

抗原

See all EDARADD 抗体
EDARADD (EDAR-Associated Death Domain (EDARADD))

适用

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宿主

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克隆类型

  • 18
多克隆

标记

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This EDARADD antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 15
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    AA 1-215

    原理

    EDARADD Rabbit pAb

    序列

    MGLRTTKQMG RGTKAPGHQE DHMVKEPVED TDPSTLSFNM SDKYPIQDTE LPKAEECDTI TLNCPRNSDM KNQGEENGFP DSTGDPLPEI SKDNSCKENC TCSSCLLRAP TISDLLNDQD LLDVIRIKLD PCHPTVKNWR NFASKWGMSY DELCFLEQRP QSPTLEFLLR NSQRTVGQLM ELCRLYHRAD VEKVLRRWVD EEWPKRERGD PSRHF

    交叉反应

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human EDARADD (NP_665860.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    EDARADD (EDAR-Associated Death Domain (EDARADD))

    别名

    EDARADD

    背景

    This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,EDARADD,ECTD11A,ECTD11B,ED3,EDA3,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,EDARADD

    分子量

    23kDa/24kDa

    基因ID

    128178

    UniProt

    Q8WWZ3

    途径

    Ubiquitin Proteasome Pathway
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