E2F5 抗体 (AA 197-346)
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- 抗原 See all E2F5 抗体
- E2F5
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抗原表位
- AA 197-346
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This E2F5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- E2F5 Rabbit pAb
- 序列
- QLEVPIPEMG QNGQKKYQIN LKSHSGPIHV LLINKESSSS KPVVFPVPPP DDLTQPSSQS LTPVTPQKSS MATQNLPEQH VSERSQALQQ TSATDISSAG SISGDIIDEL MSSDVFPLLR LSPTPADDYN FNLDDNEGVC DLFDVQILNY
- 交叉反应
- 人
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 197-346 of human E2F5 (NP_001942.2).
- 亚型
- IgG
- Top Product
- Discover our top product E2F5 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- E2F5
- 别名
- E2F5 (E2F5 产品)
- 背景
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.,E2F5,E2F-5,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,ErbB-HER Signaling Pathway,E2F5
- 分子量
- 20kDa/37kDa
- 基因ID
- 1875
- UniProt
- Q15329
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