DRAP1 抗体 (AA 50-150)
Our Local Distributor
北京 101111
Quick Overview for DRAP1 抗体 (AA 50-150) (ABIN7266844)
抗原
See all DRAP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 50-150
-
原理
- DRAP1 Rabbit pAb
-
序列
- LKKACQVTQS RNAKTMTTSH LKQCIELEQQ FDFLKDLVAS VPDMQGDGED NHMDGDKGAR RGRKPGSGGR KNGGMGTKSK DKKLSGTDSE QEDESEDTDT D
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human DRAP1 (NP_006433.2).
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))
-
别名
- DRAP1
-
背景
- Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008],NC2-alpha,DRAP1,Epigenetics & Nuclear Signaling,Transcription Factors,DRAP1
-
基因ID
- 10589
-
UniProt
- Q14919
抗原
-