This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described.,DLG3,MRX,MRX90,NEDLG,PPP1R82,SAP102,XLMR,Neuroscience,Cell Type Marker,Neuron marker,Dendrite marker,Synapse marker,DLG3