DNER 抗体 (AA 140-240)
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北京 101111
Quick Overview for DNER 抗体 (AA 140-240) (ABIN7266727)
抗原
See all DNER 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 140-240
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原理
- DNER Rabbit pAb
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序列
- PATGWTESMA PRQLQPVPAT QEPDKILPRS QATVTLPTWQ PKTGQKVVEM KWDQVEVIPD IACGNASSNS SAGGRLVSFE VPQNTSVKIR QDATASLILL W
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human DNER (NP_620711.3).
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亚型
- IgG
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anti-delta/notch-Like EGF Repeat Containing (DNER) (AA 339-583) antibody
DNER 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-delta/notch-Like EGF Repeat Containing (DNER) (AA 708-736), (C-Term) antibodyDNER 适用: 人 WB 宿主: 兔 Polyclonal RB40583 unconjugated
anti-delta/notch-Like EGF Repeat Containing (DNER) (Internal Region) antibodyDNER 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-delta/notch-Like EGF Repeat Containing (DNER) (AA 150-168) antibodyDNER 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-delta/notch-Like EGF Repeat Containing (DNER) (AA 368-476) antibodyDNER 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-delta/notch-Like EGF Repeat Containing (DNER) antibodyDNER 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-delta/notch-Like EGF Repeat Containing (DNER) (AA 368-476) antibodyDNER 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F3 unconjugated
anti-delta/notch-Like EGF Repeat Containing (DNER) antibodyDNER 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-delta/notch-Like EGF Repeat Containing (DNER) (AA 351-400) antibodyDNER 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:200 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DNER (delta/notch-Like EGF Repeat Containing (DNER))
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别名
- DNER
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背景
- DNER (Delta/Notch-like EGF-related receptor), also known as BET (brain-specific EGF-like transmembrane protein), is a type I transmembrane glycoprotein of the Notch/Delta family . In the mouse, DNER has been detected as 90, 120 and 150 kDa forms which are probably variably glycosylated .Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.DNER associates with protein tyrosine phosphatase zeta (PTP zeta ), which is the receptor of pleiotrophin (PTN). PTP zeta -PTN-DNER signaling has been implicated in the regulation of neuritogenesis. Expression of DNER in glioblastoma stem-like cells inhibits formation of neurospheres in vitro, while in vivo it induces differentiation and inhibits growth of xenografts, thus acting as a tumor suppressor.,DNER,UNQ26,bet,Neuroscience,Stem Cells,DNER
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分子量
- 78kDa
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基因ID
- 92737
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UniProt
- Q8NFT8
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途径
- Skeletal Muscle Fiber Development
抗原
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