D2HGDH 抗体 (AA 322-521)
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Quick Overview for D2HGDH 抗体 (AA 322-521) (ABIN7266669)
抗原
See all D2HGDH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 322-521
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原理
- D2HGDH Rabbit pAb
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序列
- GRHLHLASPV QESPFYVLIE TSGSNAGHDA EKLGHFLEHA LGSGLVTDGT MATDQRKVKM LWALRERITE ALSRDGYVYK YDLSLPVERL YDIVTDLRAR LGPHAKHVVG YGHLGDGNLH LNVTAEAFSP SLLAALEPHV YEWTAGQQGS VSAEHGVGFR KRDVLGYSKP PGALQLMQQL KALLDPKGIL NPYKTLPSQA
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 322-521 of human D2HGDH (NP_689996.4).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- D2HGDH (D-2-Hydroxyglutarate Dehydrogenase (D2HGDH))
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别名
- D2HGDH
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背景
- This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.,D2HGDH,D2HGD,Signal Transduction,Endocrine & Metabolism,D2HGDH
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分子量
- 32kDa/34kDa/56kDa
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基因ID
- 728294
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UniProt
- Q8N465
抗原
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