Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1) 抗体
This 兔 多克隆 antibody specifically detects Cytosolic Arginine Sensor For mTORC1 Subunit 1 in WB, IF 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7266667
发货至:
中国
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Quick Overview for Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1) 抗体 (ABIN7266667)
抗原
Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1)
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
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原理
- CASTOR1 Rabbit pAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human CASTOR1.
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亚型
- IgG
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anti-Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1) (C-Term) antibody
CASTOR1 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1)
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别名
- CASTOR1
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背景
- Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.,GATSL3,CASTOR1
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分子量
- 36kDa
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基因ID
- 652968
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UniProt
- Q8WTX7
抗原
-
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