Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1) 抗体
CASTOR1
适用: 人
IF, IHC, WB
宿主: 兔
Polyclonal
unconjugated
-
- 抗原
- Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1)
- 适用
- 人
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
- 原理
- CASTOR1 Rabbit pAb
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human CASTOR1.
- 亚型
- IgG
-
- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1)
- 别名
- CASTOR1
- 背景
- Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.,GATSL3,CASTOR1
- 分子量
- 36kDa
- 基因ID
- 652968
- UniProt
- Q8WTX7
-
You are here:
