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- 抗原 See all CARS 抗体
- CARS (Cysteinyl-tRNA Synthetase (CARS))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This CARS antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- CARS Rabbit mAb
- 交叉反应
- 人, 大鼠
- 产品特性
- Monoclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthesized peptide derived from human CARS.
- 亚型
- IgG
- Top Product
- Discover our top product CARS Primary Antibody
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anti-Cysteinyl-tRNA Synthetase (CARS) (AA 1-748) antibody
CARS 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cysteinyl-tRNA Synthetase (CARS) (AA 201-500) antibodyCARS 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl-tRNA Synthetase (CARS) antibodyCARS 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl-tRNA Synthetase (CARS) antibodyCARS 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CL2304 unconjugated
anti-Cysteinyl-tRNA Synthetase (CARS) antibodyCARS 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CL2302 unconjugated
anti-Cysteinyl-tRNA Synthetase (CARS) (AA 31-80) antibodyCARS 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl-tRNA Synthetase (CARS) (AA 661-710) antibodyCARS 适用: 人, 兔, Cow, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl-tRNA Synthetase (CARS) (AA 469-748) antibodyCARS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl-tRNA Synthetase (CARS) (C-Term) antibodyCARS 适用: 人, 小鼠, 大鼠, 兔, 犬, 马, Cow, 斑马鱼, Pig, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl-tRNA Synthetase (CARS) (N-Term) antibodyCARS 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CARS (Cysteinyl-tRNA Synthetase (CARS))
- 别名
- CARS (CARS 产品)
- 别名
- sb:cb71 antibody, CARS antibody, BcDNA:LD21177 antibody, CG8431 antibody, CRS antibody, CysRS antibody, Dmel\\CG8431 antibody, BA0089 antibody, DDBDRAFT_0215191 antibody, DDBDRAFT_0231320 antibody, DDB_0215191 antibody, DDB_0231320 antibody, DDBDRAFT_0187313 antibody, DDBDRAFT_0231318 antibody, DDB_0187313 antibody, DDB_0231318 antibody, T16B12.16 antibody, K15E6.3 antibody, K15E6_3 antibody, CARS1 antibody, CYSRS antibody, MGC:11246 antibody, CA3 antibody, cysteinyl-tRNA synthetase antibody, Cysteinyl-tRNA synthetase antibody, cysteine--tRNA ligase antibody, cysteine-tRNA ligase antibody, Cysteinyl-tRNA synthetase, class Ia family protein antibody, cysteinyl-tRNA synthetase CysS antibody, cysteinyl-tRNA synthetase S homeolog antibody, CARS antibody, cars antibody, CysRS antibody, cysS antibody, APH_RS02395 antibody, mcysS antibody, SYCO ARATH antibody, AT3G56300 antibody, AT5G38830 antibody, cars.S antibody, Cars antibody
- 背景
- Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the receptor from binding to its specific glucocorticoid response element. Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation. Thus, calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors.,CARS, CARS1, CYSRS, MGC:11246, cysteinyl-tRNA synthetase,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Nucleotide metabolism,CARS
- 分子量
- 75kDa
- 基因ID
- 833
- UniProt
- P49589
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