CDKN1C 抗体
Our Local Distributor
北京 101111
Quick Overview for CDKN1C 抗体 (ABIN7266605)
抗原
See all CDKN1C 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- CDKN1C/p57 Kip2 Rabbit mAb
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Monoclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A synthesized peptide derived from human CDKN1C/p57 Kip2
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
-
别名
- CDKN1C
-
背景
- This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010],BWCR, BWS, KIP2, WBS, p57, p57Kip2,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,Epigenetics & Nuclear Signaling,Kinase,Signal Transduction,CDKN1C
-
分子量
- 57kDa
-
基因ID
- 1028
-
UniProt
- P49918
-
途径
- Cell Division Cycle, Dopaminergic Neurogenesis
抗原
-