Cyclin H 抗体
Quick Overview for Cyclin H 抗体 (ABIN7266569)
抗原
See all Cyclin H (CCNH) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Cyclin H Rabbit mAb
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交叉反应
- 人, 小鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human Cyclin H
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cyclin H (CCNH)
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别名
- CCNH
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背景
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010],CAK, CycH, p34, p37,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cyclins,DNA Damage & Repair,Epigenetics & Nuclear Signaling,CCNH
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分子量
- 38kDa
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基因ID
- 902
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UniProt
- P51946
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
抗原
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