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Cyclin H 抗体

This anti-Cyclin H antibody is a 兔 单克隆 antibody detecting Cyclin H in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN7266569
发货至: 中国

Quick Overview for Cyclin H 抗体 (ABIN7266569)

抗原

See all Cyclin H (CCNH) 抗体
Cyclin H (CCNH)

适用

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宿主

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克隆类型

  • 64
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单克隆

标记

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This Cyclin H antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    Cyclin H Rabbit mAb

    交叉反应

    人, 小鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human Cyclin H

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Cyclin H (CCNH)

    别名

    CCNH

    背景

    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010],CAK, CycH, p34, p37,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cyclins,DNA Damage & Repair,Epigenetics & Nuclear Signaling,CCNH

    分子量

    38kDa

    基因ID

    902

    UniProt

    P51946

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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