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CAND1 抗体 (AA 750-980)

This anti-CAND1 antibody is a 兔 多克隆 antibody detecting CAND1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7266546
发货至: 中国

Quick Overview for CAND1 抗体 (AA 750-980) (ABIN7266546)

抗原

See all CAND1 抗体
CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

适用

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宿主

  • 16
  • 5

克隆类型

  • 17
  • 4
多克隆

标记

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This CAND1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 5
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    AA 750-980

    原理

    CAND1 Rabbit pAb

    序列

    GALSAMLDFF QALVVTGTNN LGYMDLLRML TGPVYSQSTA LTHKQSYYSI AKCVAALTRA CPKEGPAVVG QFIQDVKNSR STDSIRLLAL LSLGEVGHHI DLSGQLELKS VILEAFSSPS EEVKSAASYA LGSISVGNLP EYLPFVLQEI TSQPKRQYLL LHSLKEIISS ASVVGLKPYV ENIWALLLKH CECAEEGTRN VVAECLGKLT LIDPETLLPR LKGYLISGSS Y

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 750-980 of human CAND1 (NP_060918.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

    别名

    CAND1

    背景

    This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants.,CAND1,TIP120,TIP120A,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,CAND1

    分子量

    45kDa/117kDa/136kDa

    基因ID

    55832

    UniProt

    Q86VP6

    途径

    Regulation of Actin Filament Polymerization
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