CAND1 抗体 (AA 750-980)
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- 抗原 See all CAND1 抗体
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
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抗原表位
- AA 750-980
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CAND1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- CAND1 Rabbit pAb
- 序列
- GALSAMLDFF QALVVTGTNN LGYMDLLRML TGPVYSQSTA LTHKQSYYSI AKCVAALTRA CPKEGPAVVG QFIQDVKNSR STDSIRLLAL LSLGEVGHHI DLSGQLELKS VILEAFSSPS EEVKSAASYA LGSISVGNLP EYLPFVLQEI TSQPKRQYLL LHSLKEIISS ASVVGLKPYV ENIWALLLKH CECAEEGTRN VVAECLGKLT LIDPETLLPR LKGYLISGSS Y
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 750-980 of human CAND1 (NP_060918.2).
- 亚型
- IgG
- Top Product
- Discover our top product CAND1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
- 别名
- CAND1 (CAND1 产品)
- 背景
- This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants.,CAND1,TIP120,TIP120A,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,CAND1
- 分子量
- 45kDa/117kDa/136kDa
- 基因ID
- 55832
- UniProt
- Q86VP6
- 途径
- Regulation of Actin Filament Polymerization
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