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CRYAA 抗体

This anti-CRYAA antibody is a 兔 单克隆 antibody detecting CRYAA in WB 和 IF. Suitable for 人.
产品编号 ABIN7266527
发货至: 中国

Quick Overview for CRYAA 抗体 (ABIN7266527)

抗原

See all CRYAA 抗体
CRYAA (Crystallin, alpha A (CRYAA))

适用

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宿主

  • 27
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克隆类型

  • 27
  • 22
单克隆

标记

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This CRYAA antibody is un-conjugated

应用范围

  • 37
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Western Blotting (WB), Immunofluorescence (IF)
  • 原理

    CRYAA Rabbit mAb

    交叉反应

    小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human CRYAA

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CRYAA (Crystallin, alpha A (CRYAA))

    别名

    CRYAA

    背景

    Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal dominant congenital cataract (ADCC). [provided by RefSeq, Jan 2014],CRYA1, CTRCT9, HSPB4,Cell Type Marker,Neuroscience,Signal Transduction,CRYAA

    分子量

    17kDa

    基因ID

    1409

    UniProt

    P02489

    途径

    M Phase
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