CRTC2 抗体 (AA 434-693)
Quick Overview for CRTC2 抗体 (AA 434-693) (ABIN7266519)
抗原
See all CRTC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 434-693
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原理
- CRTC2 Rabbit pAb
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序列
- PLSLLAGPAD ARRSQQQLPK QFSPTMSPTL SSITQGVPLD TSKLSTDQRL PPYPYSSPSL VLPTQPHTPK SLQQPGLPSQ SCSVQSSGGQ PPGRQSHYGT PYPPGPSGHG QQSYHRPMSD FNLGNLEQFS MESPSASLVL DPPGFSEGPG FLGGEGPMGG PQDPHTFNHQ NLTHCSRHGS GPNIILTGDS SPGFSKEIAA ALAGVPGFEV SAAGLELGLG LEDELRMEPL GLEGLNMLSD PCALLPDPAV EESFRSDRLQ
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 434-693 of human CRTC2 (NP_859066.1).
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亚型
- IgG
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anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (C-Term) antibody
Verified CRTC2 适用: 人, 大鼠 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) antibodyCRTC2 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5B10 unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (pSer171) antibodyCRTC2 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 595-693) antibodyCRTC2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 180-372) antibodyCRTC2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 83-96) antibodyVerified CRTC2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 595-693) antibodyCRTC2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 542-553) antibodyVerified CRTC2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
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别名
- CRTC2
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背景
- This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5.,CRTC2,TORC-2,TORC2,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,CRTC2
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分子量
- 73kDa
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基因ID
- 200186
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UniProt
- Q53ET0
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途径
- AMPK Signaling, Carbohydrate Homeostasis
抗原
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