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CLOCK 抗体

This anti-CLOCK antibody is a 兔 单克隆 antibody detecting CLOCK in WB 和 IF. Suitable for 人.
产品编号 ABIN7266414
发货至: 中国

Quick Overview for CLOCK 抗体 (ABIN7266414)

抗原

See all CLOCK 抗体
CLOCK (Clock Homolog (Mouse) (CLOCK))

适用

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宿主

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克隆类型

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单克隆

标记

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This CLOCK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 原理

    CLOCK Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human CLOCK

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CLOCK (Clock Homolog (Mouse) (CLOCK))

    别名

    CLOCK

    背景

    The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],KAT13D, bHLHe8,Blood,Blood_Blood Pressure regulation,Cardiovascular,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Heart,Heart_Cardiac metabolism,Lipid Metabolism,Neuroscience,Signal Transduction,Transcription Factors,CLOCK

    分子量

    95kDa

    基因ID

    9575

    UniProt

    O15516

    途径

    Regulation of Lipid Metabolism by PPARalpha, Photoperiodism
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