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CMKLR1 抗体 (AA 250-350)

This anti-CMKLR1 antibody is a 兔 多克隆 antibody detecting CMKLR1 in WB 和 IF. Suitable for 人.
产品编号 ABIN7266327
发货至: 中国

Quick Overview for CMKLR1 抗体 (AA 250-350) (ABIN7266327)

抗原

See all CMKLR1 抗体
CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This CMKLR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
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    AA 250-350

    原理

    CMKLR1 Rabbit pAb

    序列

    NRLAKTKKPF KIIVTIIITF FLCWCPYHTL NLLELHHTAM PGSVFSLGLP LATALAIANS CMNPILYVFM GQDFKKFKVA LFSRLVNALS EDTGHSSYPS H

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CMKLR1 (NP_001135815.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

    别名

    CMKLR1

    背景

    Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i/G(o and beta-arrestin pathways inducing cellular responses via second messenger pathways such as intracellular calcium mobilization, phosphorylation of MAP kinases MAPK1/MAPK3 (ERK1/2, TYRO3, MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis PubMed:27716822. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2 and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism.,CMKLR1,CHEMERINR,ChemR23,DEZ,RVER1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,CMKLR1

    分子量

    42kDa

    基因ID

    1240

    UniProt

    Q99788
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