This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
CCR7
(Chemokine (C-C Motif) Receptor 7 (CCR7))
别名
CCR7
背景
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014],BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1,CDs,Cell Intrinsic Innate Immunity Signaling Pathway,G protein signaling,G protein signaling_G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,Innate Immunity_Chemokines,Signal Transduction,CCR7