CEP290 抗体 (AA 950-1050)
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北京 101111
Quick Overview for CEP290 抗体 (AA 950-1050) (ABIN7266277)
抗原
See all CEP290 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 950-1050
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原理
- CEP290 Rabbit pAb
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序列
- QKVVDNSVSL SELELANKQY NELTAKYRDI LQKDNMLVQR TSNLEHLECE NISLKEQVES INKELEITKE KLHTIEQAWE QETKLGNESS MDKAKKSITN S
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 950-1050 of human CEP290 (NP_079390.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CEP290 (Centrosomal Protein 290kDa (CEP290))
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别名
- CEP290
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背景
- This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.,CEP290,3H11Ag,BBS14,CT87,JBTS5,LCA10,MKS4,NPHP6,POC3,SLSN6,rd16,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Neuroscience,CEP290
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分子量
- 180kDa/290kDa
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基因ID
- 80184
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UniProt
- O15078
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途径
- cAMP Metabolic Process, M Phase
抗原
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