CENPE 抗体 (AA 2542-2701)
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Quick Overview for CENPE 抗体 (AA 2542-2701) (ABIN7266274)
抗原
See all CENPE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2542-2701
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原理
- CENPE Rabbit pAb
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序列
- ALILKSEHIR LEKEISKLKQ QNEQLIKQKN ELLSNNQHLS NEVKTWKERT LKREAHKQVT CENSPKSPKV TGTASKKKQI TPSQCKERNL QDPVPKESPK SCFFDSRSKS LPSPHPVRYF DNSSLGLCPE VQNAGAESVD SQPGPWHASS GKDVPECKTQ
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 2542-2701 of human CENPE (NP_001804.2).
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亚型
- IgG
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应用备注
- WB,1:200 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CENPE (Centromere Protein E, 312kDa (CENPE))
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别名
- CENPE
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背景
- Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.,CENPE,CENP-E,KIF10,MCPH13,PPP1R61,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centromere,CENPE
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分子量
- 301kDa/312kDa/316kDa
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基因ID
- 1062
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UniProt
- Q02224
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途径
- M Phase, Maintenance of Protein Location
抗原
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