CDK1/2/3 (pThr14) 抗体
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北京 101111
Quick Overview for CDK1/2/3 (pThr14) 抗体 (ABIN7266234)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr14
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原理
- Phospho-CDK1/2/3-T14 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Phosphorylated Antibodies
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纯化方法
- Affinity purification
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免疫原
- A phospho specific peptide corresponding to residues surrounding T14 of human CDK1/2/3
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亚型
- IgG
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anti-CDK1/2/3 (pThr14) antibody
适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1430 unconjugated Recombinant Antibody
anti-CDK1/2/3 (pThr14) antibody适用: 人, 小鼠, 大鼠, 猴 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CDK1/2/3 (Ser226) antibody适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CDK1/2/3 (pThr14) antibody适用: 人, 小鼠, 大鼠, 猴, 小鸡, Cow WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CDK1/2/3
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别名
- CDK1/CDK2/CDK3
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背景
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],CDC2, CDC28A, P34CDC2,Apoptosis,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Cytoskeleton_Microtubules,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,G protein signaling,G2/M DNA Damage Checkpoint,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Neurodegenerative Diseases,Neuroscience,Protein phosphorylation,Signal Transduction,CDK1/CDK2/CDK3
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分子量
- 34kDa
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基因ID
- 983, 1017, 1018
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UniProt
- P06493, P24941, Q00526
抗原
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