BAIAP2L1 抗体 (AA 198-388)
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Quick Overview for BAIAP2L1 抗体 (AA 198-388) (ABIN7265824)
抗原
See all BAIAP2L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 198-388
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原理
- BAIAP2L1 Rabbit pAb
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序列
- DKHCGFANHI HYYHLQSAEL LNSKLPRWQE TCVDAIKVPE KIMNMIEEIK TPASTPVSGT PQASPMIERS NVVRKDYDTL SKCSPKMPPA PSGRAYTSPL IDMFNNPATA APNSQRVNNS TGTSEDPSLQ RSVSVATGLN MMKKQKVKTI FPHTAGSNKT LLSFAQGDVI TLLIPEEKDG WLYGEHDVSK A
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 198-388 of human BAIAP2L1 (NP_061330.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))
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别名
- BAIAP2L1
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背景
- This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.,BAIAP2L1,IRTKS,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,BAIAP2L1
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分子量
- 56kDa
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基因ID
- 55971
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UniProt
- Q9UHR4
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途径
- Regulation of Actin Filament Polymerization
抗原
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