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ABCB7 抗体 (AA 503-753)

This anti-ABCB7 antibody is a 兔 多克隆 antibody detecting ABCB7 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN7265735
发货至: 中国

Quick Overview for ABCB7 抗体 (AA 503-753) (ABIN7265735)

抗原

See all ABCB7 抗体
ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

适用

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宿主

  • 48

克隆类型

  • 48
多克隆

标记

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This ABCB7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 503-753

    原理

    ABCB7 Rabbit pAb

    序列

    AIVGGSGSGK STIVRLLFRF YEPQKGSIYL AGQNIQDVSL ESLRRAVGVV PQDAVLFHNT IYYNLLYGNI SASPEEVYAV AKLAGLHDAI LRMPHGYDTQ VGERGLKLSG GEKQRVAIAR AILKDPPVIL YDEATSSLDS ITEETILGAM KDVVKHRTSI FIAHRLSTVV DADEIIVLDQ GKVAERGTHH GLLANPHSIY SEMWHTQSSR VQNHDNPKWE AKKENISKEE ERKKLQEEIV NSVKGCGNCS C

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 503-753 of human ABCB7 (NP_004290.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ABCB7 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))

    别名

    ABCB7

    背景

    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,ABCB7,ABC7,ASAT,Atm1p,EST140535,Signal Transduction,Endocrine & Metabolism,Stem Cells,Hematopoietic Progenitors,ABCB7

    分子量

    78kDa/82kDa

    基因ID

    22

    UniProt

    O75027

    途径

    Transition Metal Ion Homeostasis
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