ANKRD15 抗体 (AA 900-1000)
Quick Overview for ANKRD15 抗体 (AA 900-1000) (ABIN7265613)
抗原
See all ANKRD15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 900-1000
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原理
- KANK1 Rabbit pAb
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序列
- GNYLGYTCKC GGLQSGSPLS SQTSQPEQEV GTSEGKPISS LDAFPTQEGT LSPVNLTDDQ IAAGLYACTN NESTLKSIMK KKDGNKDSNG AKKNLQFVGI N
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 900-1000 of human KANK1 (NP_055973.2).
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亚型
- IgG
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anti-Ankyrin Repeat Domain 15 (ANKRD15) antibody
ANKRD15 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1773CT634-49-61 unconjugated
anti-Ankyrin Repeat Domain 15 (ANKRD15) (AA 701-800) antibodyANKRD15 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B8 unconjugated
anti-Ankyrin Repeat Domain 15 (ANKRD15) (AA 66-255) antibodyANKRD15 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))
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别名
- KANK1
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背景
- The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5,9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20.,KANK1,ANKRD15,CPSQ2,KANK,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,KANK1
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分子量
- 129kDa/147kDa
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基因ID
- 23189
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UniProt
- Q14678
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途径
- Regulation of Actin Filament Polymerization
抗原
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