ADRA2C 抗体 (AA 240-380)
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Quick Overview for ADRA2C 抗体 (AA 240-380) (ABIN7265501)
抗原
See all ADRA2C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-380
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原理
- ADRA2C Rabbit pAb
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序列
- RTRTLSEKRA PVGPDGASPT TENGLGAAAG AGENGHCAPP PADVEPDESS AAAERRRRRG ALRRGGRRRA GAEGGAGGAD GQGAGPGAAE SGALTASRSP GPGGRLSRAS SRSVEFFLSR RRRARSSVCR RKVAQAREKR F
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human ADRA2C (NP_000674.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
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别名
- ADRA2C
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背景
- Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008],ADRA2L2,ADRA2RL2,ADRARL2,ALPHA2CAR,ADRA2C,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,ADRA2C
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基因ID
- 152
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UniProt
- P18825
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途径
- EGFR Signaling Pathway, cAMP Metabolic Process
抗原
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