ADAM15 抗体
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北京 101111
Quick Overview for ADAM15 抗体 (ABIN7265434)
抗原
See all ADAM15 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ADAM15 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human ADAM15
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
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别名
- ADAM15
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背景
- The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],MDC15,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Extracellular Matrix_ADAM Protein Family,Invasion and Metastasis,Signal Transduction,Ubiquitin,ADAM15
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分子量
- 90,100kDa
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基因ID
- 8751
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UniProt
- Q13444
抗原
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