This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
ACTN2
(Actinin, alpha 2 (ACTN2))
别名
ACTN2
背景
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],CMD1AA, CMH23,Apoptosis,Cardiovascular,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Actins,Cytoskeleton_Microfilaments,Heart,Heart_Cardiac arrhythmias,Heart_Contractility,Immunology & Inflammation,Signal Transduction,T Cell Receptor Signaling Pathway,ACTN2