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Acetyl-CoA Carboxylase alpha 抗体

The 兔 单克隆 anti-Acetyl-CoA Carboxylase alpha antibody is suitable to detect Acetyl-CoA Carboxylase alpha in samples from 人. It has been validated for WB, IHC 和 IP.
产品编号 ABIN7265369
发货至: 中国
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Quick Overview for Acetyl-CoA Carboxylase alpha 抗体 (ABIN7265369)

抗原

See all Acetyl-CoA Carboxylase alpha (ACACA) 抗体
Acetyl-CoA Carboxylase alpha (ACACA)

适用

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宿主

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克隆类型

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单克隆

标记

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This Acetyl-CoA Carboxylase alpha antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 原理

    ACC1 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human ACC1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Acetyl-CoA Carboxylase alpha (ACACA)

    别名

    ACC1

    背景

    Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.,ACC, ACAC, ACC1, ACCA, ACACAD,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Warburg Effect,ACC1

    分子量

    257kDa/259kDa/265kDa/269kDa

    基因ID

    31

    UniProt

    Q13085

    途径

    AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect
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