ABI2 抗体 (AA 100-200)
Quick Overview for ABI2 抗体 (AA 100-200) (ABIN7265360)
抗原
See all ABI2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 100-200
-
原理
- ABI2 Rabbit pAb
-
序列
- HKEKVARREI GILTTNKNTS RTHKIIAPAN LERPVRYIRK PIDYTILDDI GHGVKWLLRF KVSTQNMKMG GLPRTTPPTQ KPPSPPMSGK GTLGRHSPYR T
-
交叉反应
- 人, 小鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ABI2 (NP_001269854.1).
-
亚型
- IgG
-
-
anti-Abl-Interactor 2 (ABI2) (AA 164-452) antibody
ABI2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 2 (ABI2) (AA 1-475) antibodyABI2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 2 (ABI2) (AA 1-475) antibodyABI2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Abl-Interactor 2 (ABI2) (AA 1-30), (N-Term) antibodyABI2 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB31117 unconjugated
anti-Abl-Interactor 2 (ABI2) antibodyABI2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 2 (ABI2) antibodyABI2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 2 (ABI2) (N-Term) antibodyABI2 适用: 人, 豚鼠, 兔, Cow, 犬, 马, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 2 (ABI2) (AA 1-30) antibodyABI2 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 2 (ABI2) (AA 1-30), (N-Term) antibodyABI2 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Abl-Interactor 2 (ABI2) (N-Term) antibodyABI2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- ABI2 (Abl-Interactor 2 (ABI2))
-
别名
- ABI2
-
背景
- Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation. Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge. Contributes to the regulation of actin assembly at the tips of neuron projections. In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain (By similarity. In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth (By similarity. Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface (By similarity. Also required for nascent adherens junction assembly in epithelial cells.,ABI2,ABI-2,ABI2B,AIP-1,AblBP3,SSH3BP2,argBP1,argBPIA,argBPIB,Cancer,Tumor suppressors,ABI2
-
分子量
- 44kDa/52kDa/54kDa/55kDa
-
基因ID
- 10152
-
UniProt
- Q9NYB9
抗原
-
