ABHD12 抗体 (AA 110-250)
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北京 101111
Quick Overview for ABHD12 抗体 (AA 110-250) (ABIN7265355)
抗原
See all ABHD12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-250
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原理
- ABHD12 Rabbit pAb
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序列
- YFIDLKKPQD QGLNHTCNYY LQPEEDVTIG VWHTVPAVWW KNAQGKDQMW YEDALASSHP IILYLHGNAG TRGGDHRVEL YKVLSSLGYH VVTFDYRGWG DSVGTPSERG MTYDALHVFD WIKARSGDNP VYIWGHSLGT G
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交叉反应
- 人, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 110-250 of human ABHD12 (NP_056415.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))
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别名
- ABHD12
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背景
- This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011],ABHD12A,BEM46L2,C20orf22,PHARC,dJ965G21.2,ABHD12,ABHD12
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基因ID
- 26090
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UniProt
- Q8N2K0
抗原
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