TMC1 抗体 (Extracellular)
-
- 抗原 See all TMC1 抗体
- TMC1 (Transmembrane Channel-Like 1 (TMC1))
- 抗原表位
- Extracellular
-
适用
- 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This TMC1 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Live Cell Imaging (LCI)
- 原理
- A Rabbit Polyclonal antibody to TMC1 (extracellular)
- 特异性
- Extracellular, 3rd loop.
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Rat,human - identical
- 产品特性
- Extracellular, 3rd loop
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: (C)EHDFPSWMAKILR, corresponding to amino acid residues 679 - 691 of mouse TMC1
- 亚型
- IgG
- Top Product
- Discover our top product TMC1 Primary Antibody
-
anti-Transmembrane Channel-Like 1 (TMC1) antibody
TMC1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Channel-Like 1 (TMC1) (AA 600-700) antibodyTMC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200-1:400
- 说明
-
Negative Control: BLP-TC010
Blocking Peptide: BLP-TC010
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
- 抗原
- TMC1 (Transmembrane Channel-Like 1 (TMC1))
- 别名
- TMC1 (TMC1 产品)
- 背景
-
Transmembrane Channel Like 1, Transmembrane cochlear-expressed protein 1,Transmembrane channel-like protein 1 (TMC1) is one of eight mammalian TMC genes. Proteins that belong to this family contain six transmembrane domains with both the C and N termini on the cytoplasmic side of the membrane, as well as a large loop between domains 4 and 5. This multi-pass transmembrane topologic structure suggests roles as a receptor, transporter, channel, or pump1. TMC1 and the closely related TMC2 gene are assembled as dimers2 and are expressed in neurosensory hair cells of the mouse inner ear where they appear to have a role as pore forming units in mechanoelectrical transduction. Mutations of the transmembrane channel-like 1 (TMC1) gene can cause dominant and recessive forms of deafness in humans and mice3 and hence, identification of the molecular functions of Tmc genes is broadly significant because it may provide a handle on the fundamental mechanisms that mediate human hearing and balance4.
Alternative names: Transmembrane Channel Like 1, Transmembrane cochlear-expressed protein 1 - 基因ID
- 13409
- NCBI登录号
- NM_138691
- UniProt
- Q8R4P5
- 途径
- Sensory Perception of Sound
-
