Tetraspanin 3 抗体 (Extracellular)
Quick Overview for Tetraspanin 3 抗体 (Extracellular) (ABIN7237881)
抗原
See all Tetraspanin 3 (TSPAN3) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 155-169, Extracellular
-
原理
- A Rabbit Polyclonal antibody to Tetraspanin-3 (extracellular)
-
特异性
- Extracellular, 2nd loop.
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Mouse,rat - identical
-
产品特性
- Extracellular, 2nd loop
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: (C)DWENTDWFKETKNQS, corresponding to amino acid residues 155 - 169 of human Tetraspanin-3
-
亚型
- IgG
-
-
anti-Tetraspanin 3 (TSPAN3) antibody
TSPAN3 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 3 (TSPAN3) (AA 90-117) antibodyTSPAN3 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26819 unconjugated
anti-Tetraspanin 3 (TSPAN3) (AA 90-117) antibodyTSPAN3 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 3 (TSPAN3) (AA 110-159) antibodyTSPAN3 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 豚鼠, 马, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 3 (TSPAN3) (AA 105-210) antibodyTSPAN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 3 (TSPAN3) (AA 107-213) antibodyTSPAN3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 3 (TSPAN3) (Middle Region) antibodyTSPAN3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:200-1:400
-
说明
-
Negative Control: (ABIN7237377)
Blocking Peptide: (ABIN7237377)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
-
- Tetraspanin 3 (TSPAN3)
-
别名
- TSPAN3
-
背景
-
TSPAN3, Transmembrane 4 Superfamily Member 8, TM4SF8,Tetraspanin-3, encoded by TSPAN3 gene is a membrane-spanning glycoprotein that has a role in cell migration, proliferation, and interactions between cells and extracellular matrix.As suggested by the family name, TSPANs are categorized by the presence of four trans-membrane domains, of which two are extracellular. The intracellular part includes the C and N terminal domains that can facilitate protein-protein interactions, as well as guide intracellular trafficking. TSPANs have multiple roles In the immune and vascular systems, and they act as organizers of functional microdomains and multi-subunit receptor complexes 1.Tspan3 is highly expressed in the brain and elevated in brains of Alzheimers disease (AD) patients. It was shown to interact with ADAM10, which is a marker for Alzheimer's disease 2. It was also shown to be expressed by dendritic cells (DCs) which suggests that it may be involved in the function of DCs in association with T cell stimulation 3.Its functional diversity and importance for the development and onset of various diseases makes Tetraspanin 3 an appealing research target.
Alternative names: TSPAN3, Transmembrane 4 Superfamily Member 8, TM4SF8 -
基因ID
- 10099
-
NCBI登录号
- NM_005724
-
UniProt
- O60637
抗原
-
