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STX1A 抗体 (Intracellular, N-Term)

This 兔多克隆 antibody specifically detects STX1A in WB, IHC 和 IF. It exhibits reactivity toward 大鼠.

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产品编号 ABIN7237876

发货至: 中国

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Quick Overview for STX1A 抗体 (Intracellular, N-Term) (ABIN7237876)

抗原

See all STX1A 抗体

STX1A (Syntaxin 1A (Brain) (STX1A))

适用

大鼠

宿主

兔

克隆类型

多克隆

标记

This STX1A antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product STX1A Primary Antibody

抗原表位
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14

7

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2

1

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1

1

1

1

1

1
AA 1-265, Intracellular, N-Term

原理

A Rabbit Polyclonal Antibody to Syntaxin 1

交叉反应

小鼠, 大鼠

预测反应

Human,mouse- 264,265 amino acid residues identical

产品特性

Intracellular, N-terminus

纯化方法

The serum was depleted of anti-GST antibodies by affinity chromatography on immobilized GST and then the IgG fraction was purified on immobilized antigen.

免疫原

GST fusion protein with the sequence MKDRTQELRTAKDSDDDDDVTVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKK, corresponding to amino acid residues 1-265 of rat syntaxin 1A

亚型

IgG
anti-Syntaxin 1A (Brain) (STX1A) (AA 1-251) antibody
STX1A 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B11-1A8 unconjugated

anti-Syntaxin 1A (Brain) (STX1A) (AA 1-255) antibody
STX1A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Syntaxin 1A (Brain) (STX1A) antibody
STX1A 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Syntaxin 1A (Brain) (STX1A) (AA 1-251) antibody
STX1A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Syntaxin 1A (Brain) (STX1A) (AA 1-251) antibody
STX1A 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

anti-Syntaxin 1A (Brain) (STX1A) (pSer14) antibody
STX1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Syntaxin 1A (Brain) (STX1A) (N-Term) antibody
STX1A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Syntaxin 1A (Brain) (STX1A) (AA 29-57), (N-Term) antibody
STX1A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24554 unconjugated

anti-Syntaxin 1A (Brain) (STX1A) (N-Term) antibody
STX1A 适用: 人, 小鼠, 大鼠, 猴, Pig, Hamster, 非洲爪蟾 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Syntaxin 1A (Brain) (STX1A) (Internal Region) antibody
STX1A 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, Pig, Bat, Hamster, 小鸡 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user

说明

Cited Application: IP
Negative Control: (ABIN7237335)
Blocking Peptide: (ABIN7237335)

限制

仅限研究用
状态

Lyophilized

溶解方式

25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

浓度

0.8 mg/mL

缓冲液

PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
抗原

STX1A (Syntaxin 1A (Brain) (STX1A))

别名

STX1A

背景

Synonyms: STX1A, Synaptotagmin-associated 35 kDa protein, P35A, P35-1, Neuron-specific antigen HPC-1
Description: Syntaxin 1 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein superfamily. The family includes 36 members in humans and is characterized by the SNARE motif, an evolutionarily conserved stretch of 60-70 amino acids that are arranged in heptad repeats1,2.SNARE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion1,2.SNAREs can be roughly divided into vesicular (v-SNAREs) and target (t-SNAREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cognate v-/t-SNAREs between two opposing membranes generates trans-SNARE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion.Syntaxin 1, like most SNAREs, is a type IV membrane protein with a relatively large N-terminus containing the SNARE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor1,2.Syntaxin 1 has been extensively studied for its role on neuronal and neuroendocrine cell exocytosis where it functions as the plasma membrane protein t-SNARE, which together with the vesicular v-SNARE protein VAMP and the membrane-associated SNAP-25 (synaptosome-associated protein 25 kDa), forms a trimeric, four-helical complex, which drives fusion of the two opposing bilayers1,2.Syntaxin 1 together with SNAP-25 is the target of the neurotoxin botulinum neurotoxin type C (BoNT/C) which following proteolytic degradation of the proteins causes inhibition of neurotransmitter release 3.

基因ID

116470

NCBI登录号

NM_004603

UniProt

P32851

途径

Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport