NPX1 抗体 (Secreted)
Quick Overview for NPX1 抗体 (Secreted) (ABIN7237737)
抗原
See all NPX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 197-211, Secreted
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原理
- A Rabbit Polyclonal antibody to Neuronal Pentraxin 1 (NPTX1)
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特异性
- Secreted
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat - identical, Human - 13 out of 15 amino acid residues identical
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产品特性
- Secreted
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)ERAKIESALTSLHQR, corresponding to amino acid residues 197 - 211 of mouse NPTX1
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亚型
- IgG
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anti-Neuronal Pentraxin 1 (NPX1) (AA 322-350) antibody
NPX1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB15369 unconjugated
anti-Neuronal Pentraxin 1 (NPX1) antibodyNPX1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Pentraxin 1 (NPX1) (AA 141-240) antibodyNPX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7E6 unconjugated
anti-Neuronal Pentraxin 1 (NPX1) (AA 88-227) antibodyNPX1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Pentraxin 1 (NPX1) (AA 115-364) antibodyNPX1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Pentraxin 1 (NPX1) (AA 174-203) antibodyNPX1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB8976 unconjugated
anti-Neuronal Pentraxin 1 (NPX1) (Middle Region) antibodyNPX1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Pentraxin 1 (NPX1) (Internal Region) antibodyVerified NPX1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Neuronal Pentraxin 1 (NPX1) (AA 1-432) antibodyNPX1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Neuronal Pentraxin 1 (NPX1) (AA 186-235) antibodyNPX1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:400
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说明
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Negative Control: (ABIN7236078)
Blocking Peptide: (ABIN7236078)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- NPX1 (Neuronal Pentraxin 1 (NPX1))
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别名
- NPTX1
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背景
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Neuronal Pentraxin-1, NP1,Neuronal Pentraxin 1 (NP1 or NPTX1) is a 47-50 kDa secreted glycoprotein that is expressed in the central nervous system and involved in excitatory synaptic remodeling1. The pentraxin superfamily members are made from monomers arranged in pentameric structures with a discoid shape. The family members are characterized by a 205 amino acids long conserved sequence located at C-terminal called the pentraxin domain with a shorter inner conserved sequence called the pentraxin signature 2.NP1 is preferentially expressed in the brain and is involved in glutamate receptor internalization. It is secreted pre-synaptically and implicated in excitatory synaptic and mitochondrial deficits. In addition, NP1 may represent a potential synapse-derived plasma biomarker that is able to identify alterations in excitatory synapses and early-onset Alzheimer's disease3.
Alternative names: Neuronal Pentraxin-1, NP1 -
基因ID
- 18164
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NCBI登录号
- NM_018713
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UniProt
- Q62443
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途径
- Carbohydrate Homeostasis, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, SARS-CoV-2 Protein Interactome
抗原
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