GPR84 抗体 (2nd Extracellular Loop) (PE)
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Quick Overview for GPR84 抗体 (2nd Extracellular Loop) (PE) (ABIN7237670)
抗原
See all GPR84 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- 2nd Extracellular Loop, AA 166-180
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原理
- A Rabbit Polyclonal Antibody to GPR84 (extracellular) conjugated to the fluorescent dye Phycoerythrin (PE)
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Human - 14,15 amino acid residues identical, mouse,rat - 13
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产品特性
- Extracellular, 2nd loop
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- CT(S)SFDRIRGRPYTT, corresponding to amino acid residues 166-180 of human GPR84
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亚型
- IgG
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anti-G Protein-Coupled Receptor 84 (GPR84) (AA 21-120) antibody
GPR84 适用: 人, 小鼠, 兔 WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 208-316) antibodyGPR84 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (Cytoplasmic Domain) antibodyGPR84 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (2nd Extracellular Loop), (AA 166-180) antibodyGPR84 适用: 人 WB, FACS, LCI, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (N-Term) antibodyGPR84 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (Extracellular Domain) antibodyGPR84 适用: 人, 马, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (Transmembrane Domain) antibodyGPR84 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 1-100) antibodyGPR84 适用: 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 208-316) antibodyGPR84 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) antibodyGPR84 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: The optimal concentration should be determined by the user
FC: 2.5-5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7582046)
Blocking Peptide: (ABIN7235454)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 μL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- GPR84 (G Protein-Coupled Receptor 84 (GPR84))
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别名
- GPR84
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背景
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Synonyms: G-protein coupled receptor 84, Inflammation-related G-protein coupled receptor EX33
Description: GPR84 is an orphan G-protein coupled receptor (GPCR) activated by micromolar concentrations of medium-chain fatty acids (MCFAs). MCFAs that activate GPR84 are usually with carbon chain lengths of 9-14, which couples primarily to a pertussis toxin (PTX)-sensitive Gi/o pathway. The most potent agonists of GPR84 includes decanoic acid, undecanoic acid and lauric acid. GPR84 demonstrates an important role in inflammation, immunity, and cancer1-3.GPR84 is predominantly expressed in immune system-related tissues and cells, such as bone marrow, spleen, lung, lymph nodes and brain microglia, T-cells, macrophages and glial cells. Its expression is also detected in adipocytes.Studies have shown that GPR84 activation in murine macrophage-like cell line results in high levels of LPS-stimulated IL-12 p40 production. In addition, GPR84 knockout mice display increased Th2 cytokine production1-3.
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基因ID
- 53831
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NCBI登录号
- NM_020370
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UniProt
- Q9NQS5
抗原
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