BRD8 抗体 (AA 331-430)
Quick Overview for BRD8 抗体 (AA 331-430) (ABIN716951)
抗原
See all BRD8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-430
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human BRD8
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亚型
- IgG
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anti-Bromodomain Containing 8 (BRD8) (AA 797-951) antibody
BRD8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 8 (BRD8) (N-Term) antibodyBRD8 适用: 人 WB, ChIP-seq, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 8 (BRD8) (AA 641-859) antibodyBRD8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 8 (BRD8) (AA 539-588) antibodyBRD8 适用: 人, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 8 (BRD8) (AA 33-128) antibodyBRD8 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3G8 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- BRD8 (Bromodomain Containing 8 (BRD8))
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别名
- Brd8
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背景
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Synonyms: SMAP, p120, SMAP2, Bromodomain-containing protein 8, Skeletal muscle abundant protein, Skeletal muscle abundant protein 2, Thyroid hormone receptor coactivating protein of 120 kDa, TrCP120, BRD8
Background: May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
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基因ID
- 10902
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UniProt
- Q9H0E9
抗原
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