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Myoferlin 抗体 (N-Term)

This anti-Myoferlin antibody is a 小鼠 单克隆 antibody detecting Myoferlin in WB 和 ICC. Suitable for 人.
产品编号 ABIN7233201
发货至: 中国

Quick Overview for Myoferlin 抗体 (N-Term) (ABIN7233201)

抗原

See all Myoferlin (MYOF) 抗体
Myoferlin (MYOF)

适用

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宿主

  • 8
  • 3
小鼠

克隆类型

  • 9
  • 2
单克隆

标记

  • 11
This Myoferlin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC)

克隆位点

7D2
  • 抗原表位

    • 2
    • 1
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    N-Term

    原理

    Anti-Myoferlin Mouse Monoclonal Antibody

    特异性

    This antibody recognizes human and mouse FER1L3.

    交叉反应

    人, 小鼠

    免疫原

    Synthetic peptide derived from the N-terminal domain of the human FER1L3 protein. Accession no. Q9NZM1.

    亚型

    IgG2a
  • 应用备注

    Immunoblotting: use at 1-10 μg/mL. A band of ~230 kDa is detected.
    Immunocytochemistry: use at 1- 20 μg/mL.
    These are recommended concentrations.
    Enduser should determine optimal concentrations for their applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute lyophilized antibody using ultrapure to a final concentration no less than 100 μg/mL. Reconstitution with PBS or Tris buffer is acceptable if required. Protein carrier, biocide or cryopreservative can be added as needed. Aliquot and store at -20C for longterm storage. Dilute immediately prior to use.

    缓冲液

    0.1M Tris, 0.1M glycine, 2 % sucrose

    储存条件

    -20 °C,-80 °C

    储存方法

    This product is stable for at least one (1) year at -20°C to -70°C. Reconstituted product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles.
  • 抗原

    Myoferlin (MYOF)

    别名

    MYOF

    背景

    Myoferlin,Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR (By similarity). {ECO:0000250}.,Ferlin proteins have been implicated in vesicle trafficking in a variety of physio- logical settings. All mammalian ferlins derive their names based on homology to the C. elegans protein FER-1 (FERtilization defective-1). FER1L3 (myoferlin, MYOF), has not yet been directly associated with a distinct mammalian disorder, but recent microarray and proteomic studies in the cancer literature have reported overexpression of MYOF in breast cancer specimens and relevant cell lines. Therefore, MYOF may be an important protein in breast cancer cells for their mobilization during cellular migration and/or invasion.,Cell membrane, Single-pass type II membrane protein. Nucleus membrane, Single-pass type II membrane protein. Cytoplasmic vesicle membrane, Single-pass type II membrane protein. Note=Concentrated at the membrane sites of both myoblast-myoblast and myoblast-myotube fusions. Detected at the plasmalemma in endothelial cells lining intact blood vessels (By similarity). Found at nuclear and plasma membranes. Enriched in undifferentiated myoblasts near the plasma membrane in puncate structures.,Fer-1-like protein 3

    UniProt

    Q9NZM1
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