PCDHGA1 抗体 (C-Term)
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Quick Overview for PCDHGA1 抗体 (C-Term) (ABIN7233054)
抗原
See all PCDHGA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 808-931, C-Term
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原理
- Anti-Protocadherin γ (pan) Mouse Monoclonal Antibody
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特异性
- This antibody recognizes human, mouse, and rat PCDHG-A, B, and C proteins
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交叉反应
- 人, 小鼠, 大鼠
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免疫原
- Fusion protein corresponding to aa 808-931 (C-terminal cytoplasmic constant domain) of mouse PCDHGA1. This sequence is present in all 22 PCDHG proteins.
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亚型
- IgG1
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应用备注
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Immunoblotting: use at 1-2 μg/mL. A band of ~100 kDa is detected.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their application. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- This product is stable for at least one (1) year at -20°C.
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- PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))
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别名
- Pcdhga1
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背景
- Protocadherin γ A1,The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. The gamma gene cluster includes 22 genes divided into 3 subfamilies: subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region (which includes 6 cadherin ectodomains and a trans-membrane region). The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins are believed to play a critical role in the establishment and function of specific cell-cell connections in the brain.
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UniProt
- Q91XZ0
抗原
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