Nlgn4l 抗体 (C-Term)
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Quick Overview for Nlgn4l 抗体 (C-Term) (ABIN7233051)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 782-945, C-Term
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原理
- Anti-Neuroligin-4 Mouse Monoclonal Antibody
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特异性
- This antibody recognizes mouse Neuroligin-4. It does not cross-react with other Neuroligins.
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交叉反应
- 小鼠, 大鼠
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免疫原
- Fusion protein corresponding to aa 782-945 (intracellular C-terminus) of mouse Neuroligin-4.
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亚型
- IgG1
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应用备注
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Immunoblotting: use at 1-2 μg/mL. A band of ~125-130 kDa is detected.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Enduser should determine optimal concentrations for their application. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- This product is stable for at least one (1) year at -20°C.
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- Nlgn4l (NLGN4L) (Neuroligin 4-Like (NLGN4L))
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别名
- Nlgn4l
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背景
- Neuroligin 4-like,Cell surface protein involved in cell-cell-interactions. Plays a role in the formation or maintenance of synaptic junctions via its interactions (via the extracellular domains) with neurexin family members. Plays a role in synaptic signal transmission. {PubMed:18434543, PubMed:21282647}.,Neuroligin-4 is a neuronal cell surface protein and a member of the type-B carboxylesterase- lipase protein family. Members of this family may act as splice site-specific ligands for beta- neurexins and may be involved in the formation and remodeling of central nervous system synapses. Neuroligin-4 interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants.,Cell membrane, Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane. Note=Detected at glycinergic postsynapses in retina. Detected on dendritic spines on cultured neurons.,Neuroligin-4, NL-4
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UniProt
- B0F2B4
抗原
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