Neuroligin 3 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for Neuroligin 3 抗体 (C-Term) (ABIN7233050)
抗原
See all Neuroligin 3 (NLGN3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 730-848, C-Term
-
原理
- Anti-Neuroligin-3 Mouse Monoclonal Antibody
-
特异性
- This antibody recognizes human, mouse and rat Neuroligin-3. It does not cross- react with Neuroligin-1, -2, or -4.
-
交叉反应
- 人, 小鼠, 大鼠
-
免疫原
- Fusion protein corresponding to aa 730-848 (intracellular C-terminus) of rat Neuroligin- 3. This sequence is 99
-
亚型
- IgG1
-
-
-
-
应用备注
-
Immunoblotting: use at 1-5 μg/mL. A band of ~110 kDa is detected.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their application. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- This product is stable for at least one (1) year at -20°C.
-
-
- Neuroligin 3 (NLGN3)
-
别名
- Nlgn3
-
背景
- Neuroligin-3,Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. {PubMed:17897391}.,Neuroligin-3 is a neuronal cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. It plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. It may also promote the initial formation of synapses and play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,Cell membrane, Single-pass type I membrane protein. Cell junction, synapse. Note=Detected at both glutamatergic and GABAergic synapses.,Gliotactin homolog
-
UniProt
- Q62889
-
途径
- Synaptic Membrane
抗原
-