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Neuroligin 3 抗体 (C-Term)

This anti-Neuroligin 3 antibody is a 小鼠 单克隆 antibody detecting Neuroligin 3 in WB, IHC 和 IF/ICC. Suitable for 大鼠.
产品编号 ABIN7233050
发货至: 中国

Quick Overview for Neuroligin 3 抗体 (C-Term) (ABIN7233050)

抗原

See all Neuroligin 3 (NLGN3) 抗体
Neuroligin 3 (NLGN3)

适用

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大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This Neuroligin 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)

克隆位点

S110-29
  • 抗原表位

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    AA 730-848, C-Term

    原理

    Anti-Neuroligin-3 Mouse Monoclonal Antibody

    特异性

    This antibody recognizes human, mouse and rat Neuroligin-3. It does not cross- react with Neuroligin-1, -2, or -4.

    交叉反应

    人, 小鼠, 大鼠

    免疫原

    Fusion protein corresponding to aa 730-848 (intracellular C-terminus) of rat Neuroligin- 3. This sequence is 99

    亚型

    IgG1
  • 应用备注

    Immunoblotting: use at 1-5 μg/mL. A band of ~110 kDa is detected.
    Immunofluorescence: use at 10 μg/mL.
    These are recommended concentrations.
    Endusers should determine optimal concentrations for their application.

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Dilute in PBS or medium that is identical to that used in the assay system.

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    This product is stable for at least one (1) year at -20°C.
  • 抗原

    Neuroligin 3 (NLGN3)

    别名

    Nlgn3

    背景

    Neuroligin-3,Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. {PubMed:17897391}.,Neuroligin-3 is a neuronal cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. It plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. It may also promote the initial formation of synapses and play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,Cell membrane, Single-pass type I membrane protein. Cell junction, synapse. Note=Detected at both glutamatergic and GABAergic synapses.,Gliotactin homolog

    UniProt

    Q62889

    途径

    Synaptic Membrane
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