Neuroligin 1 抗体 (C-Term)
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Quick Overview for Neuroligin 1 抗体 (C-Term) (ABIN7233049)
抗原
See all Neuroligin 1 (NLGN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 718-843, C-Term
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原理
- Anti-Neuroligin-1 Mouse Monoclonal Antibody
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特异性
- This antibody recognizes human, mouse, and rat Neuroligin-1. It does not cross- react with other Neuroligins.
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交叉反应
- 人, 小鼠, 大鼠
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免疫原
- Fusion protein corresponding to aa 718-843 (cytoplasmic C-terminus) of rat Neuroligin- 1, accession no. Q62765). This sequence is 99
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亚型
- IgG1
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anti-Neuroligin 1 (NLGN1) (AA 701-800) antibody
NLGN1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuroligin 1 (NLGN1) (AA 578-677) antibodyNLGN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Neuroligin 1 (NLGN1) (AA 51-300) antibodyNLGN1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibodyNLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 unconjugated
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (HRP)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 HRP
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (FITC)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 FITC
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (Biotin)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 Biotin
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (PE)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 PE
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (PerCP)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 PerCP
anti-Neuroligin 1 (NLGN1) (AA 718-843) antibody (APC)NLGN1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S97A-31 APC
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应用备注
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Immunoblotting: use at 1-5 μg/mL. A band of ~120 kDa is detected.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- This product is stable for at least one (1) year at -20°C.
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- Neuroligin 1 (NLGN1)
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别名
- Nlgn1
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背景
- Neuroligin-1,Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep (By similarity). The protein is involved in nervous system development. {UniProtKB:Q99K10, PubMed:15620359, PubMed:9325340}.,Neuroligin-1 is a neuronal cell surface protein and member of the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses, it participates in regulation of synaptic plasticity, and it is important in the development of long- term memory in adult mammalian amygdala. It's participation in cell-cell interactions may occur through assembly of intracellular junctions by binding of beta-neurexins. In nervous system tissue, Neuroligin-1 is observed primarily in neurons and in the spinal cord.,Cell membrane, Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density, Cell junction, synapse, synaptic cleft, Cell junction, synapse, synaptic cell membrane,Neuroligin I
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UniProt
- Q62765
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途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis
抗原
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