Metabotropic Glutamate Receptor 5 抗体 (C-Term)
Quick Overview for Metabotropic Glutamate Receptor 5 抗体 (C-Term) (ABIN7233043)
抗原
See all Metabotropic Glutamate Receptor 5 (GRM5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 824-1203, C-Term
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原理
- Anti-mGluR1/5 Glutamate Receptor Mouse Monoclonal Antibody
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特异性
- This antibody recognizes human, mouse, and rat mGluR1 and mGluR5.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein G affinity chromatography.
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免疫原
- Fusion protein corresponding to aa 824-1203 (cytoplasmic C-terminus) of rat mGluR5b (accession no. P31424).
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亚型
- IgG2a
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anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 458-580) antibody
GRM5 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1A11D10 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 367-380), (Extracellular) antibodyGRM5 适用: 大鼠 WB, IHC, IF, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 419-518) antibodyGRM5 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibodyGRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibodyGRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 unconjugated
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (HRP)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 HRP
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (HRP)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 HRP
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (FITC)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 FITC
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (FITC)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-33 FITC
anti-Glutamate Receptor, Metabotropic 5 (GRM5) (AA 824-1203) antibody (Biotin)GRM5 适用: 大鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S75-3 Biotin
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应用备注
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Immunoblotting: use at 1 μg/mL. A band of ~130 kDa is detected. Smaller fragments due to proteolysis are detected as well.
Positive control: Rat brain lysate.
These are recommended concentrations. User should determine optimal concentrations for their application. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- This antibody is stable for at least one (1) year at -20°C.
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- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
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别名
- Grm5
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背景
- Metabotropic glutamate receptor 5,G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium sPubMed:1320017, PubMed:21795692}.,The metabotropic glutamate receptors (mGluRs) are active through an indirect metabotropic process. They are members of the group C family of G-protein-coupled receptors, or GPCRs. Like all glutamate receptors, mGluRs bind glutamate which functions as an excitatory neurotransmitter. Metabotropic glutamate receptors are not ion channels. Instead, they activate biochemical cascades, leading to the modification of other proteins. This can lead to changes in the synapse's excitability. Eight different types of mGluRs, designated mGluR1 to mGluR8, are divided into groups I, II, and III. Receptor types are grouped based on receptor structure and physiological activity.,Cell membrane, Multi-pass membrane protein,mGluR5
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UniProt
- P31424
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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