Bassoon 抗体 (AA 786-1041)
Quick Overview for Bassoon 抗体 (AA 786-1041) (ABIN7233033)
抗原
See all Bassoon (BSN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 786-1041
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原理
- Anti-Bassoon Rabbit Polyclonal Antibody
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特异性
- This antibody recognizes human, mouse, and rat Bassoon. Multiple isoforms are detected.
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交叉反应
- 人, 小鼠, 大鼠
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免疫原
- Fusion protein corresponding to aa786-1041 (N-terminal) of human Bassoon (accession no. NM_003458.3).
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anti-Bassoon (BSN) antibody
BSN 适用: 大鼠, 小鼠 IHC, WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bassoon (BSN) antibodyBSN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bassoon (BSN) (AA 786-1041) antibodyBSN 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Bassoon (BSN) (AA 786-1041) antibody (HRP)BSN 适用: 人 IHC, WB 宿主: 兔 Polyclonal HRP
anti-Bassoon (BSN) (AA 786-1041) antibody (FITC)BSN 适用: 人 IHC, WB 宿主: 兔 Polyclonal FITC
anti-Bassoon (BSN) (AA 786-1041) antibody (Biotin)BSN 适用: 人 IHC, WB 宿主: 兔 Polyclonal Biotin
anti-Bassoon (BSN) (AA 786-1041) antibody (PE)BSN 适用: 人 IHC, WB 宿主: 兔 Polyclonal PE
anti-Bassoon (BSN) (AA 786-1041) antibody (APC)BSN 适用: 人 IHC, WB 宿主: 兔 Polyclonal APC
anti-Bassoon (BSN) (AA 786-1041) antibody (PerCP)BSN 适用: 人 IHC, WB 宿主: 兔 Polyclonal PerCP
anti-Bassoon (BSN) (AA 786-1041) antibody (Atto 488)BSN 适用: 人 IHC, WB 宿主: 兔 Polyclonal Atto 488
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应用备注
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Immunoblotting: use at 1 μg/mL.
Immunohistochemistry: use at 1-10 μg/mL.
Immunofluorescence: use at 1-10 μg/mL.
Positive control: Rat brain tissue lysate
These are recommended concentrations,
Enduser should determine optimal concentrations for their applications. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
- This antibody is stable for at least one (1) year at -20°C.
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- Bassoon (BSN)
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别名
- BSN
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背景
- Protein bassoon,Scaffold protein of the presynaptic cytomatrix at the active zone (CAZ) which is the place in the synapse where neurotransmitter is released (PubMed:12812759). After synthesis, participates in the formation of Golgi-derived membranous organelles termed Piccolo-Bassoon transport vesicles (PTVs) that are transported along axons to sites of nascent synaptic contacts (PubMed:19380881). At the presynaptic active zone, regulates the spatial organization of synaptic vesicle cluster, the protein complexes that execute membrane fusion and compensatory endocytosis (By similarity). Functions also in processes other than assembly such as the regulation of specific presynaptic protein ubiquitination by interacting with SIAH1 or the regulation of presynaptic autophagy by associating with ATG5 (By similarity). Mediates also synapse to nucleus communication leading to rUniProtKB:O88778, PubMed:12812759, PubMed:19380881}.,Bassoon, a 420 kDa protein, is localized at presynaptic nerve terminals and appears to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The C-terminal regions of the polyglutamine domains are of interest since abnormal amplification of this region in some human proteins, such as Huntingtin, can cause late-onset neuro- degeneration.,Cytoplasm, Cell junction, synapse, presynaptic active zone, Cytoplasm, cytoskeleton, Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane,Zinc finger protein 231
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UniProt
- Q9UPA5
抗原
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