Rho-related GTP-binding protein 抗体
Quick Overview for Rho-related GTP-binding protein 抗体 (ABIN7233029)
抗原
See all Rho-related GTP-binding protein (RhO (pan)) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Rhodopsin Mouse Monoclonal Antibody
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特异性
- This antibody recognizes the N-terminus of Rhodopsin from all mammalian species tested (human, mouse, rat, bovine, porcine), and most fish, birds, and amphibians.
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交叉反应
- Amphibian, Avian, 鱼, 哺乳动物
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免疫原
- Bovine rhodopsin
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亚型
- IgG1
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anti-Rho-related GTP-binding protein (RhO (pan)) antibody
RhO (pan) 适用: 人, 大鼠, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) (C-Term) antibodyRhO (pan) 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) antibodyRhO (pan) 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) antibodyRhO (pan) 适用: Cow WB, IHC 宿主: 小鼠 Monoclonal 1D4 unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) antibodyRhO (pan) 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) (Internal Region) antibodyRhO (pan) 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) (AA 62-93) antibodyRhO (pan) 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB52315 unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) antibodyRhO (pan) 适用: 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Rho-related GTP-binding protein (RhO (pan)) (AA 310-339), (C-Term) antibodyRhO (pan) 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB36659 unconjugated
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应用备注
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Immunoblotting: use at 1-10 μg/mL. A band of ~40 kDa is detected.
Immunohistochemistry: use at 1-10 μg/mL, paraffin-embedded and frozen.
Immunoprecipitation: use at 1-2 μg per 100-500 μg of protein.
These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: Rat eye lysate -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- This antibody is stable for at least one (1) year at -20°C.
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- Rho-related GTP-binding protein (RhO (pan))
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别名
- RHO
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背景
- Rhodopsin,Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins (PubMed:10926528, PubMed:12044163, PubMed:11972040, PubMed:16908857, PubMed:16586416, PubMed:17060607, PubMed:17449675, PubMed:18818650, PubMed:21389983, PubMed:22198838, PubMed:23579341, PubMed:25205354, PubMed:27458239). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (PubMed:1396673, PubMed:15111114). {UniProtKB:P08100, PubMed:1396673, PubMed:16586416, PubMed:16908857, PubMed:17060607, PubMed:17449675, PubMed:18818650, PubMed:21389983, PubMed:22198838, PubMed:23579341, PubMed:25205354, PubMed:27458239, PubMed:10926528, PubMed:11972040, PubMed:12044163, PubMed:15111114, PubMed:26526852}.,Rhodopsin is comprised of the protein opsin and a reversibly covalently bound cofactor, retinal. Opsin, made up of seven membrane-embedded alpha helices, binds retinal, a photoreactive chromophore, in a central pocket. In addition to being the pigment of the retina that is responsible for the formation of photoreceptor cells, rhodopsin conveys information stored in the chromophore to the surface of the molecule upon light absorption. Mutations in the rhodopsin gene lead to retinitis pigmentosa.,Membrane, Cell projection, cilium, photoreceptor outer segment
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UniProt
- P02699
抗原
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