FPR1 抗体
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北京 101111
Quick Overview for FPR1 抗体 (ABIN7232897)
抗原
See all FPR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-FPR1/2 MAb Mouse Monoclonal Antibody
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特异性
- This antibody recognizes human FPR1 at aa 305-GQDFRERLI-313 at the amino- terminal portion of the carboxyl-terminal tail. It also recognizes the same epitope in FPR2.
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交叉反应
- 人
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免疫原
- His-tagged recombinant FPR1 (human neutrophil N-formyl peptide receptor 1) expressed in and purified from Sf9 cells.
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亚型
- IgG1
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anti-Formyl Peptide Receptor 1 (FPR1) antibody
FPR1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Formyl Peptide Receptor 1 (FPR1) (AA 306-350) antibodyFPR1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Formyl Peptide Receptor 1 (FPR1) (AA 176-190) antibodyFPR1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Formyl Peptide Receptor 1 (FPR1) (C-Term) antibodyFPR1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Formyl Peptide Receptor 1 (FPR1) antibodyFPR1 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Formyl Peptide Receptor 1 (FPR1) (AA 179-192), (Extracellular) antibodyFPR1 适用: 人 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Formyl Peptide Receptor 1 (FPR1) (Extracellular Domain) antibodyFPR1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Formyl Peptide Receptor 1 (FPR1) (AA 155-204) antibodyFPR1 适用: 人 WB, ELISA, IF, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Formyl Peptide Receptor 1 (FPR1) (AA 155-204) antibodyFPR1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunoblotting: use at 1-5 μg/mL.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Enduser should determine optimal concentrations for their application. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C,-80 °C
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储存方法
- This product is stable for at least one (1)year at -20°C to -70 C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
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- FPR1 (Formyl Peptide Receptor 1 (FPR1))
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别名
- FPR1
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背景
- FMet-Leu-Phe receptor,High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520, PubMed:15210802). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium sPubMed:10514456, PubMed:15153520, PubMed:2161213, PubMed:2176894, PubMed:25109685, PubMed:10514456, PubMed:1712023, PubMed:2161213, PubMed:2176894}.,Formyl peptide receptors (FPR) are G protein-coupled receptors that are activated by different agonists included N- formylated peptides originating from bacteria and mitochondria. In humans, the FPR family includes the high affinity FPR1, the low affinity FPR2/ALX (previously known as FPRL1 or ALX) and FPR3. Human FPR1 is important for phagocyte chemotaxis, superoxide production, and degranulation, and helps direct phagocytes to sites of infection. Functional FPR1expression has been demonstrated on fibroblasts, bone marrow mesenchymal stem cells, A549 lung cells, HEP-G2 hepatoma cells, and on several types of epithelial cells.,Cell membrane,fMLP receptor, N-formyl peptide receptor, FPR, N-formylpeptide chemoattractant receptor
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UniProt
- P21462
抗原
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