CHGB 抗体 (C-Term)
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Quick Overview for CHGB 抗体 (C-Term) (ABIN7232896)
抗原
See all CHGB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 641-655, C-Term
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原理
- Anti-Chromogranin B Rabbit Polyclonal Antibody
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特异性
- This antibody recognizes human, mouse, and rat chromogranin B.
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交叉反应
- 人, 小鼠, 大鼠
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免疫原
- Synthetic peptide derived from the C-terminus (aa 641-655) of CgB (accession no. NP_001810. This sequence is identical in human, mouse, and rat CgB.
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应用备注
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Immunoblotting: use at 0.1-1.0 μg/mL
These are recommended concentrations.
Enduser should determine optimal concentrations for their applications.Although the predicted mw of CgB is ~76 kDa, the highly acidic nature of CgB causes it to run at a higher mw in SDS-PAGE.
Immunohistochemistry: use at 1-5 μg/mL. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C,-80 °C
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储存方法
- This antibody is stable for at least one (1) year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.
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- CHGB (Chromogranin B (Secretogranin 1) (CHGB))
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别名
- CHGB
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背景
- Secretogranin-1,Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.,Chromogranin B (CgB, secretogranin I) is a secretory granule matrix protein expressed in a wide variety of endocrine cells and neurons where it may have both extracellular and intracellular functions. Extracellular roles for CgB are dependent on its proteolytic processing within secretory granules to form smaller peptides that may have a role in the neuroendocrine/sympathoadrenal stress response to systemic infection, and CgB fragments may also have an autocrine inhibitory role in the release of co-stored hormones, such as insulin.,Secreted. Note=Neuroendocrine and endocrine secretory granules.,Chromogranin-B, CgB, Secretogranin I, SgI [Cleaved into: PE-11, GAWK peptide, CCB peptide]
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UniProt
- P05060
抗原
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