CHGB
适用: 人, 小鼠, 大鼠
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
宿主: 兔
Polyclonal
unconjugated
应用备注
Immunoblotting: use at 0.1-1.0 μg/mL These are recommended concentrations. Enduser should determine optimal concentrations for their applications.Although the predicted mw of CgB is ~76 kDa, the highly acidic nature of CgB causes it to run at a higher mw in SDS-PAGE. Immunohistochemistry: use at 1-5 μg/mL.
限制
仅限研究用
状态
Liquid
溶解方式
Dilute in PBS or medium that is identical to that used in the assay system.
浓度
Lot specific
缓冲液
PBS, pH 7.4
储存条件
-20 °C,-80 °C
储存方法
This antibody is stable for at least one (1) year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.
抗原
CHGB
(Chromogranin B (Secretogranin 1) (CHGB))
别名
CHGB
背景
Secretogranin-1,Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.,Chromogranin B (CgB, secretogranin I) is a secretory granule matrix protein expressed in a wide variety of endocrine cells and neurons where it may have both extracellular and intracellular functions. Extracellular roles for CgB are dependent on its proteolytic processing within secretory granules to form smaller peptides that may have a role in the neuroendocrine/sympathoadrenal stress response to systemic infection, and CgB fragments may also have an autocrine inhibitory role in the release of co-stored hormones, such as insulin.,Secreted. Note=Neuroendocrine and endocrine secretory granules.,Chromogranin-B, CgB, Secretogranin I, SgI [Cleaved into: PE-11, GAWK peptide, CCB peptide]